PACK-CXL: Corneal cross-linking for treatment of infectious keratitis
نویسندگان
چکیده
منابع مشابه
PACK-CXL: Corneal Cross-linking for Treatment of Infectious Keratitis
This article discusses corneal cross-linking (CXL) and how it transitioned from a modality for treating corneal ectatic disorders to an inventive means of treating infectious keratitis. Initially, CXL was successfully developed to halt the progression of ectatic diseases such as keratoconus, using the standard Dresden protocol. Later, indications were extended to treat iatrogenic ectasia develo...
متن کاملPACK-CXL: Corneal cross-linking in infectious keratitis.
BACKGROUND Corneal cross-linking (CXL) using ultraviolet light-A (UV-A) and riboflavin is a technique developed in the 1990's to treat corneal ectatic disorders such as keratoconus. It soon became the new gold standard in multiple countries around the world to halt the progression of this disorder, with good long-term outcomes in keratometry reading and visual acuity. The original Dresden treat...
متن کاملPACK-CXL: defining CXL for infectious keratitis.
THE CONCEPT OF CXL In 1998, the proof-of-principle for corneal collagen cross-linking (CXL) was born from such a “simple” concept. Combining ultraviolet-A light and a chromophore (vitamin B2, riboflavin), the cornea could be stiffened within a mere half hour and progressive thinning diseases such as keratoconus could be halted.1,2 Although still considered a relatively new concept, CXL is now i...
متن کاملCollagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting.
PURPOSE To investigate the efficacy and safety of corneal collagen cross-linking (CXL) with photoactivated riboflavin (photoactivated chromophore for infectious keratitis [PACK]-CXL) in the management of infectious keratitis with corneal melting. DESIGN Prospective clinical trial. PARTICIPANTS Forty eyes from 40 patients with advanced infectious keratitis and coexisting corneal melting. M...
متن کاملAntibacterial efficacy of accelerated photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL).
PURPOSE To investigate whether optimized photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL) treatment settings allow accelerating treatment while maintaining antibacterial efficacy. METHODS Staphylococcus aureus and Pseudomonas aeruginosa strains were irradiated with ultraviolet-A light of equal fluence but different intensity settings (18 mW/cm² for 5 minutes ...
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ژورنال
عنوان ژورنال: Journal of Ophthalmic and Vision Research
سال: 2015
ISSN: 2008-322X
DOI: 10.4103/2008-322x.156122